Research Articles
Advanced Low NSA Coatings for SPR Sensor Chips: Enhancing Sensitivity and Specificity in Biomedical Analysis
Surface Plasmon Resonance (SPR) biosensors are powerful label-free tools for real-time biomolecular interaction analysis, but their performance in complex media is severely hampered by non-specific adsorption (NSA).
Strategies for Molecularly Imprinted Polymers with Reduced Non-Specific Binding: From Synthesis to Application
This article provides a comprehensive overview of advanced strategies to minimize non-specific binding in molecularly imprinted polymers (MIPs), a critical challenge limiting their efficacy in analytical and biomedical applications.
Antifouling Peptide Coatings for Electrochemical Biosensors: Enhancing Stability and Sensitivity in Complex Biofluids
This article provides a comprehensive review of the latest advancements in electrochemical biosensors integrated with antifouling peptide coatings.
Surface-Initiated ATRP for Antifouling Surfaces: Mechanisms, Applications, and Advanced Design in Biomedical Research
This article comprehensively reviews the application of surface-initiated atom transfer radical polymerization (SI-ATRP) for developing advanced antifouling surfaces.
PEG Coatings for Protein Resistance: Mechanisms, Optimization, and Next-Generation Alternatives
This article provides a comprehensive analysis of polyethylene glycol (PEG) coatings as a cornerstone technology for minimizing non-specific protein adsorption in biomedical applications.
BSA vs. Casein: A Guide to Blocking Agent Selection for High-Performance Microfluidic Biosensors
Blocking agents are critical for minimizing non-specific binding and ensuring the sensitivity and accuracy of microfluidic biosensors.
Advanced Self-Assembled Monolayers for Eliminating Non-Specific Adsorption on Gold Surfaces in Biomedical Sensing
This article provides a comprehensive resource for researchers and drug development professionals on utilizing self-assembled monolayers (SAMs) to combat non-specific adsorption (NSA) on gold surfaces.
Zwitterionic Polymer Brushes: Revolutionizing Antifouling Biosensors for Biomedical Applications
This article comprehensively explores the application of zwitterionic polymer brushes in creating advanced antifouling biosensor surfaces.
Surface Roughness and Non-Specific Adsorption: Mechanisms, Mitigation, and Impact on Biosensor Performance
Non-specific adsorption (NSA) is a critical barrier to the reliability of biosensors and biomedical devices, with surface roughness being a key yet often overlooked factor.
Non-Specific Adsorption: Mechanisms, Impacts, and Strategies to Overcome False Positives in Diagnostic Assays
This article provides a comprehensive analysis of non-specific adsorption (NSA) as a critical source of false positives in diagnostic testing.